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Abstract

We report a record high pertussis epidemic in Denmark since August 2023. Highest incidence was in adolescents, while peak incidence in infants was lower vs previous epidemics in 2019 and 2016. Among infants aged 0–2 months, over half (29/48) were hospitalised and one infant died, underlining the disease severity in the youngest. To protect infants, pertussis vaccination in pregnant women was introduced in January 2024 in the national vaccination programme. Improved vaccination surveillance in pregnant women is being implemented.

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/content/10.2807/1560-7917.ES.2024.29.14.2400160
2024-04-04
2024-04-29
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2024.29.14.2400160
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References

  1. Decker MD, Edwards KM. Pertussis (Whooping Cough). J Infect Dis. 2021;224(12) Suppl 2;S310-20.  https://doi.org/10.1093/infdis/jiaa469  PMID: 34590129 
  2. Indenrigs- og Sundhedsministeriet. Sundhedsstyrelsens bekendtgørelse om anmeldelse af smitsomme sygdomme: BEK nr. 1260 af 27/10 2023. [Executive Order on notification of communicable diseases. The Danish Health Authority’s executive order no. 1260 of 27/1]. Copenhagen; Danish Health Authority, 2023. Danish. Available from: https://www.sst.dk/-/media/Udgivelser/2023/Smitsomme-sygdomme/Vejledning-om-anmeldelse-af-smitsomme-sygdomme.ashx
  3. Dalby T, Andersen PH, Hoffmann S. Epidemiology of pertussis in Denmark, 1995 to 2013. Euro Surveill. 2016;21(36):30334.  https://doi.org/10.2807/1560-7917.ES.2016.21.36.30334  PMID: 27632433 
  4. Nordholm AC, Søborg B, Jokelainen P, Lauenborg Møller K, Flink Sørensen L, Grove Krause T, et al. Mycoplasma pneumoniae epidemic in Denmark, October to December, 2023. Euro Surveill. 2024;29(2):2300707.  https://doi.org/10.2807/1560-7917.ES.2024.29.2.2300707  PMID: 38214084 
  5. Munkstrup C, Lomholt FK, Emborg HD, Møller KL, Krog JS, Trebbien R, et al. Early and intense epidemic of respiratory syncytial virus (RSV) in Denmark, August to December 2022. Euro Surveill. 2023;28(1):2200937.  https://doi.org/10.2807/1560-7917.ES.2023.28.1.2200937  PMID: 36695451 
  6. Emborg HD, Carnahan A, Bragstad K, Trebbien R, Brytting M, Hungnes O, et al. Abrupt termination of the 2019/20 influenza season following preventive measures against COVID-19 in Denmark, Norway and Sweden. Euro Surveill. 2021;26(22):1.  https://doi.org/10.2807/1560-7917.ES.2021.26.22.2001160  PMID: 34085632 
  7. Nielsen RT, Dalby T, Emborg HD, Larsen AR, Petersen A, Torpdahl M, et al. COVID-19 preventive measures coincided with a marked decline in other infectious diseases in Denmark, spring 2020. Epidemiol Infect. 2022;150:e138.  https://doi.org/10.1017/S0950268822001145  PMID: 35899864 
  8. Statens Serum Institut (SSI). Increase in the occurrence of whooping cough. Copenhagen: SSI; 2023. Available: https://en.ssi.dk/news/epi-news/2023/no-27---2023
  9. Merdrignac L, Acosta L, Habington A, Garcìa Cenoz M, Pandolfi E, Fabiánová K, et al. Effectiveness of pertussis vaccination in pregnancy to prevent hospitalisation in infants aged <2 months and effectiveness of both primary vaccination and mother’s vaccination in pregnancy in infants aged 2-11 months. Vaccine. 2022;40(44):6374-82.  https://doi.org/10.1016/j.vaccine.2022.09.054  PMID: 36182617 
  10. Danish Health Authority. Indstilling til indførelse af permanent tilbud om kighostevaccination til gravide. [Recommendation for the introduction of a permanent offer of pertussis vaccination to pregnant women]. Copenhagen: Danish Health Authority; 2023. Danish. Available from: https://www.sundhedsstyrelsen.dk/-/media/Nyheder/2023/Endelig-indstilling-kighostevaccination-til-gravide_250423-_2_.ashx?sc_lang=da&hash=9EED24C08C59494EFF744B168ADC2F69
  11. Causey K, Fullman N, Sorensen RJD, Galles NC, Zheng P, Aravkin A, et al. Estimating global and regional disruptions to routine childhood vaccine coverage during the COVID-19 pandemic in 2020: a modelling study. Lancet. 2021;398(10299):522-34.  https://doi.org/10.1016/S0140-6736(21)01337-4  PMID: 34273292 
  12. Statens Serum Institut (SSI). Monitoring in numbers, graphs and maps. DiTeKiPolHiB1 (3 months), Vaccination coverage. Copenhagen: SSI. [Accessed: 3 Apr 2024]. Available from: https://statistik.ssi.dk//sygdomsdata#!/?vaccination=1&sex=3&landsdel=100&xaxis=Cohort&show=Graph&datatype=Vaccination
  13. Cohen R, Ashman M, Taha MK, Varon E, Angoulvant F, Levy C, et al. Pediatric Infectious Disease Group (GPIP) position paper on the immune debt of the COVID-19 pandemic in childhood, how can we fill the immunity gap? Infect Dis Now. 2021;51(5):418-23.  https://doi.org/10.1016/j.idnow.2021.05.004  PMID: 33991720 
  14. The Ministry of Social Affairs and Children and The Ministry of Health. En endnu stærkere vaccinationsindsats. De mange skal beskytte de få. [An even stronger vaccination effort: the many must protect the few]. Copenhagen; The Ministry of Social Affairs and Children, and The Ministry of Health; 2018. Danish. Available from: https://www.ft.dk/samling/20181/almdel/SUU/bilag/49/1958120.pdf
  15. Wendelboe AM, Van Rie A, Salmaso S, Englund JA. Duration of immunity against pertussis after natural infection or vaccination. Pediatr Infect Dis J. 2005;24(5) Suppl;S58-61.  https://doi.org/10.1097/01.inf.0000160914.59160.41  PMID: 15876927 
  16. Domenech de Cellès M, Magpantay FM, King AA, Rohani P. The pertussis enigma: reconciling epidemiology, immunology and evolution. Proc Biol Sci. 2016;283(1822):20152309.  https://doi.org/10.1098/rspb.2015.2309  PMID: 26763701 
  17. European Centre for Disease Prevention and Control (ECDC). Communicable disease threats report, 17 December - 23 December 2023, week 48. Stockholm: ECDC; 2023. Available from: https://www.ecdc.europa.eu/en/publications-data/communicable-disease-threats-report-17-23-december-2023-week-51
  18. Seppälä E, Bråthen Kristoffersen A, Bøås H, Frimann Vestrheim D, Greve-Isdahl M, Freiesleben De Blasio B, et al. Pertussis epidemiology including direct and indirect effects of the childhood pertussis booster vaccinations, Norway, 1998-2019. Vaccine. 2022;40(23):3142-9.  https://doi.org/10.1016/j.vaccine.2022.04.038  PMID: 35469697 
  19. Bhavsar A, Mertsola J, Poulsen A, Silfverdal SA. Pertussis in infants in Nordic countries. Acta Paediatr. 2021;110(7):2040-4.  https://doi.org/10.1111/apa.15800  PMID: 33555063 
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